Peptidergic Regulation of Homeostasis.

V.Havinson, I.Kvetnoy, V.Yuzhakov, V.Popuchiev, S.Konovalov. Publishing house ‘Nauka’. Saint Petersburg, 2003. 195 p.

In modern biology and medicine, the investigations of the role of the signal molecules in the mechanisms that maintain homeostasis have a special value. This issue is extremely important, because the study of the mechanisms that are the basis of regulating the processes of vitality enables us to solve more effectively the problems of diagnosis, cure and prevention of many diseases. Peptidergic regulation of the co-ordinate function of different organs and systems is achieved thanks to the strictly regulated activity of many endocrine and non-endocrine cells, which, while they produce peptide regulators and other short-range peptide messengers, ensure vital processes at a level corresponding to the evolutionary and genetic status of a living system.

This monograph is an attempt to analyse in detail for the first time the role and meaning of regulatory peptides in the regulation of homeostasis in a normal state, and also some common pathological processes and the aging of the body. The data for the book, obtained in the course of many years of original research under the supervision, and with the participation, of authors in different laboratories and institutes, have no analogue and are high-priority research themes.

S. S. Konovalov